Objective: to describe and compare the structure characteristics of enamel in human severely Fluorotic teeth from water-drinking endemic fluorosis area and coal-burning endemic fluorosis area. 摘要目的:描述并比较燃煤污染型和饮水型氟中毒地区重度氟斑牙釉质结构特点。
Objective To investigate the expression of BMP-2 in mice incisor enamel organ cells under chronic fluoride exposure and elucidate the mechanism of dental fluorosis. 目的观察慢性氟中毒对小鼠切牙成釉细胞骨形成蛋白-2(BMP-2)表达的影响,探讨氟斑牙的致病机制。
The clinical manifestation of enamel fluorosis is the chalk to fuscescent plaques on enamel of the teeth that erupt during the same period. Enamel defects can be seen in severe cases. 其临床表现为同一时期萌出的牙齿釉质上出现白垩色到褐色的斑块,严重者有釉质缺损。
This study added new research contents to biological mechanism of enamel fluorosis and renewed the mechanism of fluoride affecting ameloblasts biological characteristics at the chloride channels point of view. 本研究为氟斑牙的生物学产生机理增加了新的研究内容,从氯离子通道的角度重新审视了氟离子影响成釉细胞生物学特性的机制。
Enamel fluorosis is the most frequent symptom in early chronic fluorosis. The main cause which results in enamel fluorosis is due to long-time overtaking of fluoride during the development of enamel. 氟斑牙是慢性氟中毒早期最常见的症状,产生氟斑牙最主要的原因是机体在釉质发育期间长期摄入了过量的氟,导致釉质发育障碍。